Ando Hiroshige, late 1830s, chuban yokoye published by Sanoki-Kyoka Edition
Shinagawa developed into an important town in the early 1600s after the construction of the Tokaido, the principal route connecting Edo (modern day Tokyo) and Kyoto, and Shinagawa was the first of fifty-three post towns along the way after departing from Nihonbashi. Post towns provided food and lodgings for travelers, much like the hotels of Shinagawa do nowadays.
Ando Hiroshige ,”sunrise” (hinode, 日の出), Hoeidō (保永堂) edition
Shinagawa-shuku (品川宿 Shinagawa-shuku?) was the one of the fifty-three stations of the Tōkaidō. It is located in Shinagawa. It was located in the present-day Shinagawa Port area near Shinagawa Station.
A street of houses backing on to the seashore, and the tail-end of a daimyo’s procession passing along it; behind the houses ships moored in the bay.
Being the first station on the highway, Shinagawa was thronged with travellers coming and going. The road was lined with many teahouses, restaurants and entertainment quarters. The bay, seen in Hiroshige’s picture, has been reclaimed and now forms a part of Tokyo.
more about Shinagawa in present times.